Heterogeneity of Type I diabetes: analysis of monozygotic twins in Great Britain and the United States

@article{Redondo2001HeterogeneityOT,
  title={Heterogeneity of Type I diabetes: analysis of monozygotic twins in Great Britain and the United States},
  author={Maria Jose Redondo and Liang Yu and Mohammed Hawa and Todd Mackenzie and David A. Pyke and George S. Eisenbarth and R David Leslie},
  journal={Diabetologia},
  year={2001},
  volume={44},
  pages={354-362}
}
Aims. To determine the risk, hazard rate and factors affecting progression to diabetes in monozygotic twins of patients with Type I (insulin-dependent) diabetes mellitus. Methods. Prospective analysis was done of two cohorts of non-diabetic monozygotic twins of patients with Type I diabetes from Great Britain (n = 134) and the United States (n = 53). Results. The diabetes-free survival analysis was similar between both cohorts (p = 0.6). The combined survival analysis (n = 187, median follow-up… CONTINUE READING
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