Heterogeneity of TERT promoter mutations status in squamous cell carcinomas of different anatomical sites.

@article{Cheng2015HeterogeneityOT,
  title={Heterogeneity of TERT promoter mutations status in squamous cell carcinomas of different anatomical sites.},
  author={Katherine A Cheng and Boaz Kurtis and Sabina Babayeva and Jian Zhuge and Irlna I. Tantchou and Dongming Cai and Rocco J. Lafaro and John T. Fallon and Minghao Zhong},
  journal={Annals of diagnostic pathology},
  year={2015},
  volume={19 3},
  pages={146-8}
}
Squamous cell carcinoma (SCC) can arise from different anatomical sites including the skin, head and neck, lung, esophagus, genital area, and so on. Despite the same histopathologic features and immunohistochemistry profile, the SCCs of different body sites can show tremendous differences in their presenting symptoms, risk factor associations, natural history, prognosis, and response to treatment. This may reflect the fact that SCCs are heterogenous and likely have unique molecular… CONTINUE READING