Heterogeneity of T-Tubules in Pig Hearts

  title={Heterogeneity of T-Tubules in Pig Hearts},
  author={Hanne C. Gadeberg and Richard C. Bond and Cherrie H. T. Kong and Guillaume P. A. Chanoit and Raimondo Ascione and Mark B. Cannell and Andrew F James},
  booktitle={PloS one},
BACKGROUND T-tubules are invaginations of the sarcolemma that play a key role in excitation-contraction coupling in mammalian cardiac myocytes. Although t-tubules were generally considered to be effectively absent in atrial myocytes, recent studies on atrial cells from larger mammals suggest that t-tubules may be more numerous than previously supposed. However, the degree of heterogeneity between cardiomyocytes in the extent of the t-tubule network remains unclear. The aim of the present study… CONTINUE READING

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