Heterogeneity of Human Lactoferrin Due to Differences in Sialic Acid Content


Extract: Differences in sialic acid content and not genetic polymorphism determine the observed electrophoretic heterogeneity of human lactoferrin, the iron-binding protein of external secretions. Lactoferrin molecules have at least one to four sialic acid residues. The asialo derivative is electrophoretically homogeneous.Speculation: As with other nonhuman… (More)
DOI: 10.1203/00006450-197110000-00003


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