Heterogeneity of Human CD4(+) T Cells Against Microbes.

@article{Sallusto2016HeterogeneityOH,
  title={Heterogeneity of Human CD4(+) T Cells Against Microbes.},
  author={Federica Sallusto},
  journal={Annual review of immunology},
  year={2016},
  volume={34},
  pages={
          317-34
        }
}
CD4(+) T helper (Th) cells play a central role in the adaptive immune response by providing help to B cells and cytotoxic T cells and by releasing different types of cytokines in tissues to mediate protection against a wide range of pathogenic microorganisms. These functions are performed by different types of Th cells endowed with distinct migratory capacities and effector functions. Here we discuss how studies of the human T cell response to microbes have advanced our understanding of Th cell… CONTINUE READING
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