Heterogeneity of Escherichia coli phages encoding Vero cytotoxins: comparison of cloned sequences determining VT1 and VT2 and development of specific gene probes.

@article{Willshaw1987HeterogeneityOE,
  title={Heterogeneity of Escherichia coli phages encoding Vero cytotoxins: comparison of cloned sequences determining VT1 and VT2 and development of specific gene probes.},
  author={Geraldine A. Willshaw and Henry R. Smith and Sylvia M. Scotland and A. M. Field and Bernard Rowe},
  journal={Journal of general microbiology},
  year={1987},
  volume={133 5},
  pages={1309-17}
}
Phages coding for production of Vero cytotoxins VT1 or VT2 in strains of Escherichia coli serotype O157.H7 or O157.H- were morphologically indistinguishable. Their genome size and restriction enzyme digests of the phage DNA were similar. These phages were clearly different in these respects from a VT1-encoding phage isolated from a strain of E. coli O26.H11 (H19). However the VT1 region cloned from the phage originating in the E. coli O157.H7 strain was identical to the VT1 region previously… CONTINUE READING

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