Heterogeneity in the effect of different ixodid tick species on human natural killer cell activity.

@article{Kube2002HeterogeneityIT,
  title={Heterogeneity in the effect of different ixodid tick species on human natural killer cell activity.},
  author={Miroslav Kube{\vs} and Paul{\'i}na Koc{\'a}kov{\'a} and Mirko Slov{\'a}k and Monika Sl{\'a}vikov{\'a} and Norbert Fuchsberger and Patricia A Nuttall},
  journal={Parasite immunology},
  year={2002},
  volume={24 1},
  pages={23-8}
}
Tick saliva plays a vital role in blood-feeding, including manipulation of the host response to tick infestation. Furthermore, a diverse number of tick-borne pathogens are transmitted to vertebrate hosts via tick saliva, some of which exploit the immunomodulatory activities of their vector's saliva. We report that salivary gland extracts (SGE) derived from Dermacentor reticulatus adult ticks induce a decrease in the natural killer (NK) activity of effector cells obtained from healthy human… CONTINUE READING

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