Heterogeneity in the B1 (CD20) cell surface molecule expressed by human B-lymphocytes.

@article{Tedder1988HeterogeneityIT,
  title={Heterogeneity in the B1 (CD20) cell surface molecule expressed by human B-lymphocytes.},
  author={Thomas F. Tedder and Garry J McIntyre and Stuart F. Schlossman},
  journal={Molecular immunology},
  year={1988},
  volume={25 12},
  pages={
          1321-30
        }
}
The B1 molecule (CD20) is a phosphoprotein expressed only by B-lymphocytes. In this study, analysis of B1 immunoprecipitated from surface iodinated B-cell lines and B-lymphocytes has shown that there are several expressed forms of B1. A predominant species of Mr 33,000 represents 75-80% of the iodinated cell surface B1 and a Mr 35,000 species represents 20-25%. Limited proteinase digestion of these two species generated similar peptide maps demonstrating that the different forms of B1 shared… CONTINUE READING
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