Heterogeneity in ampR-ampC gene interaction in Enterobacter cloacae.

@article{Goering1988HeterogeneityIA,
  title={Heterogeneity in ampR-ampC gene interaction in Enterobacter cloacae.},
  author={Richard Goering and Christine C. Sanders and William E. Sanders and Robert Guay and Sandrine Gu{\'e}rin},
  journal={Reviews of infectious diseases},
  year={1988},
  volume={10 4},
  pages={786-92}
}
The ampR gene and its regulation of AmpC beta-lactamase synthesis were investigated for Enterobacter cloacae 1194E, a wild-type strain producing a group A (pI 8.7) enzyme. Expression of the cloned E. cloacae 1194E ampR-ampC region was examined initially in Escherichia coli HB101. However, transformants showed only constitutive beta-lactamase expression. For study of enzyme expression in a more closely related host, the cloned E. cloacae 1194E ampR-ampC region was transformed into E. cloacae 55… CONTINUE READING