Heterodyne frequency-domain multispectral diffuse optical tomography of breast cancer in the parallel-plane transmission geometry.

  title={Heterodyne frequency-domain multispectral diffuse optical tomography of breast cancer in the parallel-plane transmission geometry.},
  author={Han Y. Ban and Martin Schweiger and Venkaiah C. Kavuri and Jeffrey M. Cochran and L. Xie and David R. Busch and Jaka Katrasnik and Saurav Pathak and Stephanie Histed Chung and K. H. Lee and Regine Choe and Brian J. Czerniecki and Simon Robert Arridge and Arjun G. Yodh},
  journal={Medical physics},
  volume={43 7},
PURPOSE The authors introduce a state-of-the-art all-optical clinical diffuse optical tomography (DOT) imaging instrument which collects spatially dense, multispectral, frequency-domain breast data in the parallel-plate geometry. METHODS The instrument utilizes a CCD-based heterodyne detection scheme that permits massively parallel detection of diffuse photon density wave amplitude and phase for a large number of source-detector pairs (10(6)). The stand-alone clinical DOT instrument thus… 

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