Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer

@article{Rovito2005HeterocyclicAA,
  title={Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer},
  author={Peter M Rovito and P. N. Dias Morse and K Spinek and Nancy E. Newman and Richard F. Jones and Catherine Y. Wang and Gabriel P. Haas},
  journal={Prostate Cancer and Prostatic Diseases},
  year={2005},
  volume={8},
  pages={69-74}
}
A variety of carcinogenic heterocyclic amines are produced during the cooking of meat at high temperatures. These carcinogens are metabolized by N-acetyltransferases (NAT), which are polymorphic in the population. This study examined associations between prostate cancer (PCa) and the consumption of different kinds of meat, heterocyclic amine intake and NAT genotypes. PCa patients and controls were recruited in the Syracuse, NY area. Levels of meat and heterocyclic amine intakes were determined… CONTINUE READING
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Increased NAT2 activity is associated with prostate cancer risk

  • LD Ratnasinghe
  • Proc Am Assoc Cancer Res
  • 2003

Association of prostate cancer with rapid N - acetyltransferase 1 ( NAT 1 * 10 ) in combination with slow N - acetyltransferase 2 acetylator genotypes in a pilot case – control study

  • LD Ratnasinghe
  • Environ Mol Mutagen
  • 2002

Correlation of the genotypes for N-acetyltransferases 1 and 2 with double bladder and prostate cancers in a case-comparison study

  • CY Wang
  • Anticancer Res
  • 2002

Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas

  • N Ishibe
  • Pharmacogenetics
  • 2002

A prospective study on intake of animal products and risk of prostate cancer

  • DS Michaud
  • Cancer Causes Control
  • 2001

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