Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer

  title={Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer},
  author={Peter M Rovito and P. N. Dias Morse and K Spinek and Nancy E. Newman and Richard F. Jones and Catherine Y. Wang and Gabriel P. Haas},
  journal={Prostate Cancer and Prostatic Diseases},
A variety of carcinogenic heterocyclic amines are produced during the cooking of meat at high temperatures. These carcinogens are metabolized by N-acetyltransferases (NAT), which are polymorphic in the population. This study examined associations between prostate cancer (PCa) and the consumption of different kinds of meat, heterocyclic amine intake and NAT genotypes. PCa patients and controls were recruited in the Syracuse, NY area. Levels of meat and heterocyclic amine intakes were determined… CONTINUE READING
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