Heterochromatin protein 2 interacts with Nap-1 and NURF: a link between heterochromatin-induced gene silencing and the chromatin remodeling machinery in Drosophila.

@article{Stephens2006HeterochromatinP2,
  title={Heterochromatin protein 2 interacts with Nap-1 and NURF: a link between heterochromatin-induced gene silencing and the chromatin remodeling machinery in Drosophila.},
  author={Gena E. Stephens and Hua Qiao Xiao and Dirk-H Lankenau and Carl Wu and Sarah C. R. Elgin},
  journal={Biochemistry},
  year={2006},
  volume={45 50},
  pages={
          14990-9
        }
}
Heterochromatin protein 2 (HP2) is a nonhistone chromosomal protein from Drosophila melanogaster that binds to heterochromatin protein 1 (HP1) and has been implicated in heterochromatin-induced gene silencing. Heretofore, HP1 has been the only known binding partner of HP2, a large protein devoid of sequence motifs other than a pair of AT hooks. In an effort to identify proteins that interact with HP2 and assign functions to its various domains, nuclear proteins were fractionated under… CONTINUE READING

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The nucleosome remodeling factor.

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NAP-1, Nucleosome assembly protein 1, a histone chaperone involved in Drosophila telomeres.

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