Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells

@inproceedings{Zeng2013HeterochromatinP1,
  title={Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells},
  author={An Zeng and Yong-Qin Li and Chen Wang and Xiao-Shuai Han and Ge Li and Jian-yong Wang and Dang-sheng Li and Yong-wen Qin and Yufang Shi and Gary Brewer and Qing Jing},
  booktitle={The Journal of cell biology},
  year={2013}
}
Adult stem cells (ASCs) capable of self-renewal and differentiation confer the potential of tissues to regenerate damaged parts. Epigenetic regulation is essential for driving cell fate decisions by rapidly and reversibly modulating gene expression programs. However, it remains unclear how epigenetic factors elicit ASC-driven regeneration. In this paper, we report that an RNA interference screen against 205 chromatin regulators identified 12 proteins essential for ASC function and regeneration… CONTINUE READING
Highly Cited
This paper has 59 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

60 Citations

02040'13'14'15'16'17'18
Citations per Year
Semantic Scholar estimates that this publication has 60 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Similar Papers

Loading similar papers…