Heterochromatin protein 1 is recruited to various types of DNA damage

Abstract

Heterochromatin protein 1 (HP1) family members are chromatin-associated proteins involved in transcription, replication, and chromatin organization. We show that HP1 isoforms HP1-alpha, HP1-beta, and HP1-gamma are recruited to ultraviolet (UV)-induced DNA damage and double-strand breaks (DSBs) in human cells. This response to DNA damage requires the chromo… (More)
DOI: 10.1083/jcb.200810035

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Cite this paper

@inproceedings{Luijsterburg2009HeterochromatinP1, title={Heterochromatin protein 1 is recruited to various types of DNA damage}, author={Martijn S. Luijsterburg and Christoffel Dinant and Hannes Lans and Jan Stap and Elzbieta Wiernasz and Saskia Lagerwerf and Dani{\"e}l O. Warmerdam and Michael Lindh and Maartje C. Brink and Jurek W. Dobrucki and Jacob A. Aten and Maria Fousteri and Gert Jansen and Nico P Dantuma and Wim Vermeulen and Leon H. F. Mullenders and Adriaan B. Houtsmuller and Pernette J. Verschure and Roel van Driel}, booktitle={The Journal of cell biology}, year={2009} }