Heterochromatin and tri-methylated lysine 20 of histone H4 in animals

  title={Heterochromatin and tri-methylated lysine 20 of histone H4 in animals},
  author={Niki Kourmouli and P. Jeppesen and Shantha Mahadevhaiah and P. Burgoyne and Rong Wu and D. Gilbert and S. Bongiorni and G. Prantera and L. Fanti and S. Pimpinelli and W. Shi and R. Fundele and P. Singh},
  journal={Journal of Cell Science},
  pages={2491 - 2501}
  • Niki Kourmouli, P. Jeppesen, +10 authors P. Singh
  • Published 2004
  • Biology, Medicine
  • Journal of Cell Science
  • Tri-methylated lysine 20 on histone H4 (Me(3)K20H4) is a marker of constitutive heterochromatin in murine interphase and metaphase cells. Heterochromatin marked by Me(3)K20H4 replicates late during S phase of the cell cycle. Serum starvation increases the number of cells that exhibit high levels of Me(3)K20H4 at constitutive heterochromatin. Me(3)K20H4 is also present at the centromeric heterochromatin of most meiotic chromosomes during spermatogenesis and at the pseudoautosomal region, as well… CONTINUE READING
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