Heterochromatin and gene expression in Drosophila.

  title={Heterochromatin and gene expression in Drosophila.},
  author={Karen S. Weiler and Barbara T. Wakimoto},
  journal={Annual review of genetics},
Heterochromatin is both necessary for the expression of heterochromatic genes and inhibitory for the expression of euchromatic genes. These two properties of heterochromatin have been elucidated from the study of chromosome rearrangements that induce position effect variegation (PEV) in Drosophila melanogaster. Novel euchromatin-heterochromatin junctions can affect the expression of euchromatic and heterochromatic genes located several megabases away, distinguishing higher order chromatin… CONTINUE READING
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