Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals

@article{Cowell2002HeterochromatinHA,
  title={Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals},
  author={Ian G. Cowell and Rebecca L. Aucott and Shantha K Mahadevaiah and Paul S. Burgoyne and Neville S. Huskisson and Silvia Bongiorni and Giorgio Prantera and Laura Fanti and Sergio Pimpinelli and Rong Y Wu and David M. Gilbert and Wei W. Shi and Reinald H. Fundele and H. Boyd Morrison and P. G. Jeppesen and Prim B. Singh},
  journal={Chromosoma},
  year={2002},
  volume={111},
  pages={22-36}
}
We show that methylated lysine 9 of histone H3 (Me9H3) is a marker of heterochromatin in divergent animal species. It localises to both constitutive and facultative heterochromatin and replicates late in S-phase of the cell cycle. Significantly, Me9H3 is enriched in the inactive mammalian X chromosome (Xi) in female cells, as well as in the XY body during meiosis in the male, and forms a G-band pattern along the arms of the autosomes. Me9H3 is a constituent of imprinted chromosomes that are… CONTINUE READING
Highly Influential
This paper has highly influenced 13 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 99 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 115 references

Acetylation - dependent associations of histones H 3 / H 4 with HP 1

  • H Polioudaki, N Kourmouli, +4 authors SD Georgatos
  • EMBO Rep
  • 2001

Isolation and culture of mouse preimplantation embryos

  • HP Pratt
  • 2001

Similar Papers

Loading similar papers…