Heterochromatic genes in Drosophila: a comparative analysis of two genes.

  title={Heterochromatic genes in Drosophila: a comparative analysis of two genes.},
  author={Sandra R. Schulze and Bryant F. McAllister and Donald Sinclair and Kathleen A. Fitzpatrick and Marcella Marchetti and Sergio Pimpinelli and Barry M. Honda},
  volume={173 3},
Centromeric heterochromatin comprises approximately 30% of the Drosophila melanogaster genome, forming a transcriptionally repressive environment that silences euchromatic genes juxtaposed nearby. Surprisingly, there are genes naturally resident in heterochromatin, which appear to require this environment for optimal activity. Here we report an evolutionary analysis of two genes, Dbp80 and RpL15, which are adjacent in proximal 3L heterochromatin of D. melanogaster. DmDbp80 is typical of… CONTINUE READING

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