Heterochiral N-formyl methionyl peptides. Molecular conformation and crystal structures of N-f-L-Met-D-Phe and N-f-L-Met-D-Phe-OtBu.

@article{Eggleston1988HeterochiralNM,
  title={Heterochiral N-formyl methionyl peptides. Molecular conformation and crystal structures of N-f-L-Met-D-Phe and N-f-L-Met-D-Phe-OtBu.},
  author={D. Eggleston},
  journal={International journal of peptide and protein research},
  year={1988},
  volume={31 2},
  pages={
          164-72
        }
}
  • D. Eggleston
  • Published 1988
  • Chemistry, Medicine
  • International journal of peptide and protein research
Crystal and molecular structures for the heterochiral sequence N-formyl-l-methionine-d-phenylalanine, 1, and its tertiary butyl ester, 2, are reported. The solid-state peptide conformation is compared to that observed in solution by n.m.r. techniques. For N-f-Met-d-Phe, 1, the crystal was orthorhombic, space group P21 2121 with a cell of dimensions a = 5.061(3), b = 16.575(5) and c = 19.656(6) A at ambient temperature of 293K; V = 1649(2)A3, Z = 4, Dm= 1.31(2)gcm−3, Dx= 1.307gcm−3, μ(Mokx) = 2… Expand
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