Hesperidin as an inhibitor of lipases from porcine pancreas and Pseudomonas.

@article{Kawaguchi1997HesperidinAA,
  title={Hesperidin as an inhibitor of lipases from porcine pancreas and Pseudomonas.},
  author={Ken Kawaguchi and Takafumi Mizuno and Kaoru Aida and Katsuyoshi Uchino},
  journal={Bioscience, biotechnology, and biochemistry},
  year={1997},
  volume={61 1},
  pages={102-4}
}
In the course of our screening work for new types of lipase inhibitors, hesperidin was identified as a simple and small molecular weight inhibitor in the peels of Citrus unshiu. Hesperidin inhibited lipase activity from porcine pancreas and that from Pseudomonas, and their IC50 was 32 and 132 micrograms/ml, respectively. Hesperidin, neohesperidin, narirutin, and naringin are known as the main flavonoids in Citrus unshiu. Neohesperidin also inhibited the lipase from procine pancreas, but did not… CONTINUE READING