Hesperidin, a flavanoglycone attenuates experimental diabetic neuropathy via modulation of cellular and biochemical marker to improve nerve functions

@article{Visnagri2014HesperidinAF,
  title={Hesperidin, a flavanoglycone attenuates experimental diabetic neuropathy via modulation of cellular and biochemical marker to improve nerve functions},
  author={Asjad Visnagri and A. Kandhare and Shalendra Chakravarty and P. Ghosh and S. Bodhankar},
  journal={Pharmaceutical Biology},
  year={2014},
  volume={52},
  pages={814 - 828}
}
Abstract Aim: Diabetic neuropathy (DN) is one of the most common long-term complications of diabetes mellitus and clinically can be characterized by an elevated nociceptive response with electrophysiological conduction abnormalities. The present investigation was designed to evaluate the neuroprotective effect of hesperidin against STZ induced diabetic neuropathic pain in laboratory rats. Materials and methods: DN was induced in Sprague–Dawley rats (150–200 g) by intraperitoneal administration… Expand

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