Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1.

@article{Marsters1997HerpesvirusEM,
  title={Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1.},
  author={Scot A. Marsters and T M Ayres and M. Skubatch and Christa L. Gray and Mike Rothe and Avi Ashkenazi},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 22},
  pages={14029-32}
}
The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Based on an expressed sequence tag, we have cloned a cDNA encoding a novel member of the human TNFR family. A closely related protein, designated HVEM (for herpesvirus entry mediator), was identified independently by another group as a mediator of herpesvirus entry into mammalian cells (Montgomery, R., Warner, M., Lum, B., and Spear, P… CONTINUE READING
Highly Influential
This paper has highly influenced 15 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 113 extracted citations

TNF Receptor-Associated Factor (TRAF) Signaling Network in CD4(+) T-Lymphocytes.

The Tohoku journal of experimental medicine • 2015
View 8 Excerpts
Highly Influenced

Tumor Necrosis Factor ( TNF ) – a and TNF Receptors in Viral Pathogenesis ( 44487 )

GEORGESHERBEIN, WILLIAM A. O’BRIEN
-1
View 8 Excerpts
Highly Influenced

Isolation, molecular cloning, and characterization of a novel porcine lymphotoxin beta receptor gene.

Genetics and molecular research : GMR • 2014
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…