Herpesviral infection and Toll-like receptor 2

@article{Cai2012HerpesviralIA,
  title={Herpesviral infection and Toll-like receptor 2},
  author={Ming-sheng Cai and Mei-li Li and Chun-fu Zheng},
  journal={Protein & Cell},
  year={2012},
  volume={3},
  pages={590-601}
}
In the last decade, substantial progress has been made in understanding the molecular mechanisms involved in the initial host responses to viral infections. Herpesviral infections can provoke an inflammatory cytokine response, however, the innate pathogen-sensing mechanisms that transduce the signal for this response are poorly understood. In recent years, it has become increasingly evident that the Toll-like receptors (TLRs), which are germline-encoded pattern recognition receptors (PRRs… CONTINUE READING

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