Herpes simplex.

  title={Herpes simplex.},
  author={Pamela Chayavichitsilp and Joseph V Buckwalter and Andrew C Krakowski and Sheila F. Friedlander},
  journal={Pediatrics in review},
  volume={30 4},
          119-29; quiz 130
After completing this article, readers should be able to: 1. Characterize the epidemiology of herpes simplex virus (HSV) infection, including mode of transmission, incubation period, and period of communicability. 2. Recognize the difference in clinical manifestations of HSV1 and HSV2 infection. 3. Diagnose various manifestations of HSV infection. 4. Describe the difference in the clinical manifestations and outcome of HSV infection in newborns and older infants and children. 5. Discuss the… 

Congenital herpes simpleх: modern approach to prevention, diagnosis, and treatment

The analysis showed that despite the recurrent course of genital herpes in 4 out of 5 women during pregnancy, none of the pregnant women had a laboratory examination for HSV, pregnant women did not receive systemic etiological therapy and all deliveries were natural, contributing to the early development of severe forms of neonatal herpes.

Seroprevalence of Herpes Simplex virus types 1 and 2 and their Association with CD4 count among HIV-positive patients

Investigation of the seroprevalence of HSV type 1 and HSV-2 in HIV-positive patients compare with the rate in HIV -negative patients and to evaluate their association with CD4 count found high with no correlation withCD4 count.

Risk of severe herpes simplex virus infection in systemic lupus erythematosus: analysis of epidemiology and risk factors analysis in Taiwan

Patients with SLE are at higher risk of severe HSV infection, and related risk factors include being older than 18 years, having a history of HSV mucocutaneous infection, recent receipt of steroid pulse therapy and a daily oral dose of steroid over 7.5 mg prednisolone.

[Morphological diagnosis of viral damage to a kidney transplant].

The principles of differential diagnosis of kidney transplant damage caused by viral infections and that with acute cellular and humoral rejection are described, which plays an important role due to opposite approaches to treating these diseases.

Current Antivirals and Novel Botanical Molecules Interfering With Herpes Simplex Virus Infection

Currently available anti-herpetic therapies, novel molecules being assessed in clinical trials and new botanical compounds reported in the last 20 years with antiviral activities against HSVs that might represent future treatments against these viruses are reviewed.

HSV-1 as well as HSV-2 is frequent in oral mucosal lesions of children on chemotherapy

In a novel finding, real-time PCR detected copies of HSV-2 in 69 % cases, all missed by conventional PCR, which is commonly shed from oral mucosal lesions in children receiving chemotherapy.


The hypothesis that EBV and CMV coinfections drive HIV-1 disease progression and the development of HIV-associated non-Hodgkin’s lymphoma is supported and the results suggest that GBV-C plays a protective role against theDevelopment of non-hodgkins lymphoma in HIV- 1 positive individuals.

HSV-1 infection and pathogenesis in the tree shrew eye following corneal inoculation

Support of the tree shrew as a non-human primate HSK model, which could be useful for mechanistic studies of HSK, is discussed.



Herpes simplex virus infections

  • R. Reichman
  • Medicine, Biology
    European Journal of Clinical Microbiology
  • 2005
The physical properties and mode of replication of HSV are briefly described, and an outline of the different clinical manifestations associated with HSV infection is presented.

Management of Neonatal Herpes Simplex Virus Infection

High rates of morbidity and mortality in disseminated infections, followed by central nervous system infection and the least in SEM infection are seen, however, SEM infection is associated with poor developmental outcome even in infants who do not have encephalitis, and the prognosis for this infection is considerably improved.

Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review.

Information on age- and sex-specific prevalence of herpes simplex virus (HSV) types 2 and 1 infections is essential to optimize genital herpes control strategies, which increase in importance because

Herpes simplex virus type 2 in the United States, 1976 to 1994.

Improvements in the prevention of HSV-2 infection are needed, particularly since genital ulcers may facilitate the transmission of the human immunodeficiency virus.

Third trimester antiviral prophylaxis for preventing maternal genital herpes simplex virus (HSV) recurrences and neonatal infection.

Women with recurrent genital herpes simplex virus should be informed that the risk of neonatal herpes is low and Antenatal antiviral prophylaxis reduces viral shedding and recurrences at delivery and reduces the need for cesarean delivery for genital herpes.

Sexually transmitted diseases treatment guidelines, 2006.

  • K. WorkowskiS. Berman
  • Medicine
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports
  • 2006
These guidelines for the treatment of persons who have sexually transmitted diseases (STDs) were developed by CDC after consultation with a group of professionals knowledgeable in the field of STDs