Herpes simplex virus type 1-induced interferon production and activation of natural killer cells in mice.

Abstract

Cultures of peritoneal exudate cells (PEC) of non-immune C57BL/6 mice reacted to infectious herpes simplex virus type 1 (HSV), but not to non-infectious virions by producing interferon. Similarly, when the virus preparations were injected intraperitoneally (i.p.) and interferon was determined in the wash-out fluid, interferon could only be detected after… (More)

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@article{Kirchner1983HerpesSV, title={Herpes simplex virus type 1-induced interferon production and activation of natural killer cells in mice.}, author={H. Kirchner and Harald Engler and Christian Schr{\"o}der and Rainer Zawatzky and Eric A. Storch}, journal={The Journal of general virology}, year={1983}, volume={64 (Pt 2)}, pages={437-41} }