Herpes simplex virus infections

@article{Whitley2001HerpesSV,
  title={Herpes simplex virus infections},
  author={R. Whitley and B. Roizman},
  journal={The Lancet},
  year={2001},
  volume={357},
  pages={1513-1518}
}
Herpes simplex virus (HSV) is a member of the herpesviridae family. Recognised since ancient Greek times, the virus frequently infects human beings, causing a range of diseases from mild uncomplicated mucocutaneous infection to those that are life threatening. In the past 50 years, substantial advances in our knowledge of the molecular biology of HSV have led to insights into disease pathogenesis and management. This review provides a contemporary interpretation of the biological properties… Expand
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  • 2020
Genital herpes simplex virus infections are among the most prevalent sexually transmitted infections in the United States. It continues to be a public health concern because of its recurrent natureExpand
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Recurrent oral ulceration caused by HSV-1 may be seen by the general dental practitioner and can cause significant morbidity. Expand
Herpesvirus infection of the liver.
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  • Medicine
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The clinical presentation of hepatic herpesvirus infection is often nonspecific, and a high index of suspicion and rapid progression to liver biopsy to document viral replication or outgrowth of virus-infected cells can lead to lifesaving therapeutic interventions. Expand
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This chapter reviews the clinical disease, traditional and evolving medical and surgical therapeutic options, and future directions in prevention strategies, including development of vaccination. Expand
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