Herpes simplex virus infections

@article{Whitley2001HerpesSV,
  title={Herpes simplex virus infections},
  author={R. Whitley and B. Roizman},
  journal={The Lancet},
  year={2001},
  volume={357},
  pages={1513-1518}
}
Herpes simplex virus (HSV) is a member of the herpesviridae family. Recognised since ancient Greek times, the virus frequently infects human beings, causing a range of diseases from mild uncomplicated mucocutaneous infection to those that are life threatening. In the past 50 years, substantial advances in our knowledge of the molecular biology of HSV have led to insights into disease pathogenesis and management. This review provides a contemporary interpretation of the biological properties… Expand
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Herpes simplex virus.
TLDR
The clinician must maintain a high index of suspicion with neonates, children, and adults, as HSV can often mimic other CNS diseases and prompt initiation of treatment is integral. Expand
Therapeutic options for herpes simplex infections
TLDR
To expand the scope of available treatments, efforts have focused on the development of vaccines against herpes simplex virus and new agents such as immune response modifiers, and data suggest that these new agents are promising in their therapeutic potential. Expand
Neonatal Herpes Simplex Virus Infection
TLDR
Clinicians must be astute, because early diagnosis and early treatment are key to a better prognosis, and many neonates now are effectively treated and experience no or fewer long-term sequelae of this potentially devastating infection. Expand
Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management.
TLDR
The epidemiology, pathogenesis, and diagnostic features of HSV infections are reviewed, providing the clinician with an up-to-date understanding of the available management strategies for mucocutaneous HSV-induced disease. Expand
Herpes Simplex Virus: Epidemiology, Diagnosis, and Treatment.
  • S. Cole
  • Medicine
  • The Nursing clinics of North America
  • 2020
Genital herpes simplex virus infections are among the most prevalent sexually transmitted infections in the United States. It continues to be a public health concern because of its recurrent nature… Expand
Recurrent intra-oral herpes simplex 1 infection.
TLDR
Recurrent oral ulceration caused by HSV-1 may be seen by the general dental practitioner and can cause significant morbidity. Expand
Herpesvirus infection of the liver.
  • J. Fingeroth
  • Medicine
  • Infectious disease clinics of North America
  • 2000
TLDR
The clinical presentation of hepatic herpesvirus infection is often nonspecific, and a high index of suspicion and rapid progression to liver biopsy to document viral replication or outgrowth of virus-infected cells can lead to lifesaving therapeutic interventions. Expand
Ocular Herpes Simplex
TLDR
This chapter reviews the clinical disease, traditional and evolving medical and surgical therapeutic options, and future directions in prevention strategies, including development of vaccination. Expand
Pathogenesis of herpes simplex virus infections of the cornea
TLDR
The major laboratory advances of the past 20 years have enabled a torrent of new insights into the biological properties of HSV, including the latest member, HHV-8, which was only identified last decade. Expand
Marine organisms as a therapeutic source against herpes simplex virus infection.
TLDR
An overview of potential anti-HSV agents derived from marine organisms and their promising application in HSV therapy is presented. Expand
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References

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