Herpes simplex virus 1 counteracts viperin via its virion host shutoff protein UL41.


The interferon (IFN)-inducible viperin protein restricts a broad range of viruses. However, whether viperin plays a role during herpes simplex virus 1 (HSV-1) infection is poorly understood. In the present study, it was shown for the first time that wild-type (WT) HSV-1 infection couldn't induce viperin production, and ectopically expressed viperin… (More)
DOI: 10.1128/JVI.01380-14


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