Herpes simplex thymidine kinase (HStk) transgenic donor lymphocytes

Abstract

Patients with recurrent leukemia after an allogeneic hematopoietic stem cell transplant may be treated with donor lymphocyte infusions (DLI). The transfusion of lymphocytes from the original hematopoietic stem cell donor induces remission in approximately one third of relapsed AML cases and 80% of relapsed CML. DLI may be complicated by delayed and… (More)
DOI: 10.1038/sj.bmt.1702020

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