Herpes gestationis autoantibodies recognize a 180-kD human epidermal antigen.

  title={Herpes gestationis autoantibodies recognize a 180-kD human epidermal antigen.},
  author={Lynne Morrison and R. S. Labib and John J. Zone and Luis A Diaz and Grant J. Anhalt},
  journal={The Journal of clinical investigation},
  volume={81 6},
Herpes gestationis (HG) is a putative autoimmune bullous dermatosis of pregnancy which shares many findings with bullous pemphigoid (BP), a disease of the elderly. This study identifies for the first time the antigen detected by HG autoantibodies and compares it with that recognized by BP autoantibodies. Sera from 16 HG and 17 BP patients, and from normal pregnant women were evaluated by immunofluorescent (IF) studies and immunoblotted against human epidermal extracts. 89% of HG sera with… CONTINUE READING
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