Herp depletion inhibits zearalenone-induced cell death in RAW 264.7 macrophages.

@article{Chen2016HerpDI,
  title={Herp depletion inhibits zearalenone-induced cell death in RAW 264.7 macrophages.},
  author={Fenglei Chen and Pengfei Lin and Nan Wang and Diqi Yang and Xin Wen and Dong Zhou and Aihua Wang and Yaping Jin},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2016},
  volume={32},
  pages={115-22}
}
Herp is an endoplasmic reticulum (ER) membrane protein and strongly induced by the ER stress that not only participates in the unfolded protein response (UPR) under the ER stress, but also in cell autophagy under glucose starvation (GS). However, we do not know whether Herp plays any roles in other responses, such as zearalenone (ZEA). In this study, we constructed recombinant lentiviral vectors for Herp shRNA expression and generated stable Herp knockdown RAW 264.7 macrophages. Flow cytometry… CONTINUE READING
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Mycotoxin zearalenone induces AIF- and ROS-mediated cell death through p53- and MAPK-dependent signaling pathways in RAW264.7 macrophages.

Toxicology in vitro : an international journal published in association with BIBRA • 2011
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