Heroin addiction in African Americans: a hypothesis-driven association study.

@article{Levran2009HeroinAI,
  title={Heroin addiction in African Americans: a hypothesis-driven association study.},
  author={Orna Levran and Douglas Londono and Kimberly O'Hara and Matthew Randesi and John Rotrosen and Paul Casadonte and Shirley Linzy and J{\"u}rg Ott and Miriam Adelson and Mary Jeanne Kreek},
  journal={Genes, brain, and behavior},
  year={2009},
  volume={8 5},
  pages={
          531-40
        }
}
Heroin addiction is a chronic complex disease with a substantial genetic contribution. This study was designed to identify gene variants associated with heroin addiction in African Americans. The emphasis was on genes involved in reward modulation, behavioral control, cognitive function, signal transduction and stress response. We have performed a case-control association analysis by screening with 1350 variants of 130 genes. The sample consisted of 202 former severe heroin addicts in methadone… CONTINUE READING

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