Heritable variation of ERBB2 and breast cancer risk.


Amplification of the epithelial growth factor receptor gene ERBB2 (HER2, NEU) in breast cancer is associated with a poor clinical prognosis. In mammary gland development, this receptor plays a role in ductal and lobuloalveolar differentiation. We conducted a systematic investigation of the role of genetic variation of the ERBB2 gene in breast cancer risk in… (More)
DOI: 10.1158/1055-9965.EPI-08-1202

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