Heritable variation of ERBB2 and breast cancer risk.

Abstract

Amplification of the epithelial growth factor receptor gene ERBB2 (HER2, NEU) in breast cancer is associated with a poor clinical prognosis. In mammary gland development, this receptor plays a role in ductal and lobuloalveolar differentiation. We conducted a systematic investigation of the role of genetic variation of the ERBB2 gene in breast cancer risk in… (More)
DOI: 10.1158/1055-9965.EPI-08-1202

4 Figures and Tables

Topics

  • Presentations referencing similar topics