Heritable gene targeting in zebrafish using customized TALENs

@article{Huang2011HeritableGT,
  title={Heritable gene targeting in zebrafish using customized TALENs},
  author={Peng Huang and An Xiao and Mingguo Zhou and Zuoyan Zhu and Shuo Lin and Bo Zhang},
  journal={Nature Biotechnology},
  year={2011},
  volume={29},
  pages={699-700}
}
699 To the Editor: Studies of targeted gene modifications are of great interest in basic research as well as for clinical and agricultural applications1. In the February issue of Nature Biotechnology, two articles reported genomic modifications using transcription activator-like (TAL) effectors2,3. Using fusion proteins, each comprising a TAL effector DNA binding domain and a FokI cleavage domain, Miller et al.2 reported that TAL effector nucleases (TALENs) successfully disrupted target genes… 

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