Heritable Variation, With Little or No Maternal Effect, Accounts for Recurrence Risk to Autism Spectrum Disorder in Sweden

@article{Yip2018HeritableVW,
  title={Heritable Variation, With Little or No Maternal Effect, Accounts for Recurrence Risk to Autism Spectrum Disorder in Sweden},
  author={Benjamin Hon Kei Yip and Dan Bai and Behrang Mahjani and Lambertus Klei and Yudi Pawitan and Christina M. Hultman and Dorothy E. Grice and Kathryn Roeder and Joseph D. Buxbaum and Bernie J Devlin and Abraham Reichenberg and Sven Sandin},
  journal={Biological Psychiatry},
  year={2018},
  volume={83},
  pages={589-597}
}
BACKGROUND Autism spectrum disorder (ASD) has both genetic and environmental origins, including potentially maternal effects. Maternal effects describe the association of one or more maternal phenotypes with liability to ASD in progeny that are independent of maternally transmitted risk alleles. While maternal effects could play an important role, consistent with association to maternal traits such as immune status, no study has estimated maternal, additive genetic, and environmental effects in… CONTINUE READING
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