Heritability of childhood weight gain from birth and risk markers for adult metabolic disease in prepubertal twins.

@article{Beardsall2009HeritabilityOC,
  title={Heritability of childhood weight gain from birth and risk markers for adult metabolic disease in prepubertal twins.},
  author={Kathryn Beardsall and Ken K Ong and Nuala Murphy and Marion L. Ahmed and Jing Hua Zhao and Maarten Peeters and David B Dunger},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2009},
  volume={94 10},
  pages={3708-13}
}
OBJECTIVE Associations between size at birth, postnatal weight gain, and potential risk for adult disease have been variably explained by in utero exposures or genetic risk that could affect both outcomes. We utilized a twin model to explore these hypotheses. METHODS One hundred pairs of healthy twins aged 8.9 yr (range, 7.2-10.9 yr) had fasting blood samples collected, blood pressure (BP) measured, and anthropometry assessed. All measurements were converted to sd scores (SDS) to adjust for… CONTINUE READING

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