Heritability of carotid artery atherosclerotic lesions: an ultrasound study in 154 families.

@article{Moskau2005HeritabilityOC,
  title={Heritability of carotid artery atherosclerotic lesions: an ultrasound study in 154 families.},
  author={Susanna Moskau and Astrid Golla and C. Grothe and Monika Boes and Christoph Pohl and Thomas Klockgether},
  journal={Stroke},
  year={2005},
  volume={36 1},
  pages={5-8}
}
BACKGROUND AND PURPOSE Ultrasound examination of the carotid arteries yields several quantitative measures that may serve as intermediate phenotypes in genetic studies. This study was undertaken to compare the heritabilities of 3 ultrasound measures: intima-media thickness (IMT), plaque score, and maximal stenosis. METHODS We studied 565 individuals from 154 families ascertained by an affected parent with carotid artery atherosclerosis. IMT, plaque score, and maximal stenosis of the carotid… CONTINUE READING
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