Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register

@article{Hilker2018HeritabilityOS,
  title={Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register},
  author={Rikke W. Hilker and Dorte Helenius and Birgitte Fagerlund and Axel E Skytthe and Birte Yding Glenth\oj},
  journal={Biological Psychiatry},
  year={2018},
  volume={83},
  pages={492-498}
}
BACKGROUND Twin studies have provided evidence that both genetic and environmental factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples have varied methodologically. This study provides updated heritability estimates based on nationwide twin data and an improved statistical methodology. METHODS Combining two nationwide registers, the Danish Twin Register and the Danish Psychiatric Research Register, we identified a sample of twins born between 1951 and… CONTINUE READING

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