Heritability of Malaria in Africa

@article{Mackinnon2005HeritabilityOM,
  title={Heritability of Malaria in Africa},
  author={Margaret J Mackinnon and Tabitha Wanja Mwangi and Robert W. Snow and Kevin Marsh and Thomas N Williams},
  journal={PLoS Medicine},
  year={2005},
  volume={2},
  pages={316 - 319}
}
BACKGROUND While many individual genes have been identified that confer protection against malaria, the overall impact of host genetics on malarial risk remains unknown. METHODS AND FINDINGS We have used pedigree-based genetic variance component analysis to determine the relative contributions of genetic and other factors to the variability in incidence of malaria and other infectious diseases in two cohorts of children living on the coast of Kenya. In the first, we monitored the incidence of… CONTINUE READING

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