Heritability of BDNF alleles and their effect on brain morphology in schizophrenia.

@article{Wassink1999HeritabilityOB,
  title={Heritability of BDNF alleles and their effect on brain morphology in schizophrenia.},
  author={Thomas H. Wassink and Jeffrey J Nelson and Raymond R. Crowe and Nancy C. Andreasen},
  journal={American journal of medical genetics},
  year={1999},
  volume={88 6},
  pages={724-8}
}
Accumulating evidence suggests that disturbed brain development may play a role in the etiology of schizophrenia, and that the illness is, to a significant degree, heritable. We therefore investigated brain derived neurotrophic factor (BDNF), a neurotrophin expressed in fetal brain, as a candidate disease gene for schizophrenia. We also investigated the effect of BDNF on adult brain morphology. All subjects were diagnosed by DSM-IIIR or DSM-IV criteria with schizophrenia spectrum disorders… CONTINUE READING