Heritability and complex segregation analysis of hypoadrenocorticism in the standard poodle.

@article{Famula2003HeritabilityAC,
  title={Heritability and complex segregation analysis of hypoadrenocorticism in the standard poodle.},
  author={Thomas R Famula and Janelle M. Belanger and Anita M. Oberbauer},
  journal={The Journal of small animal practice},
  year={2003},
  volume={44 1},
  pages={8-12}
}
The heritability of hypoadrenocorticism (Addison's disease) was evaluated in 778 standard poodles with known Addisonian phenotypes. Addisonian status was confirmed clinically by adrenocorticotropic hormone (ACTH) challenge and 8.6 per cent of the poodles enrolled in the study were classified as being Addisonian. Hypoadrenocorticism affected both sexes with equal probability (P > 0.1). The most common coat colours had a negligible effect on the incidence of hypoadrenocorticism (P > 0.09… CONTINUE READING

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