Hereditary vascular anomalies: new insights into their pathogenesis.

  title={Hereditary vascular anomalies: new insights into their pathogenesis.},
  author={J-C Tille and Michael Sean Pepper},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={24 9},
Increased understanding of the mechanisms of angiogenesis and lymphangiogenesis has provided a glimpse at some of the molecules involved in the pathophysiology of hemangiomas and vascular malformations. This review focuses on recent advances in our understanding of the mechanisms of angiogenesis/lymphangiogenesis and the differentiation of arterial, venous, and lymphatic vessels. We integrate this knowledge with new data obtained from genetic studies in humans, which have revealed a number of… CONTINUE READING


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