Hereditary spastic paraplegias: an update

@article{Depienne2007HereditarySP,
  title={Hereditary spastic paraplegias: an update},
  author={Christel Depienne and Giovanni Stevanin and Alexis Brice and Alexandra Durr},
  journal={Current Opinion in Neurology},
  year={2007},
  volume={20},
  pages={674–680}
}
Purpose of reviewHereditary spastic paraplegias are a genetically heterogeneous group of diseases. Recent advances concerning their nosology and molecular bases have greatly improved the genetic diagnosis of these diseases, with implications for genetic counselling. The recent identification of new genes and loci, however, has blurred the distinction between hereditary spastic paraplegias and other entities, such as cerebellar ataxias or leucodystrophies. Cerebral MRI and the familial history… 
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