Hereditary nonpolyposis colorectal cancer (Lynch syndrome II). Diploid malignancies with prolonged survival.

@article{Frei1992HereditaryNC,
  title={Hereditary nonpolyposis colorectal cancer (Lynch syndrome II). Diploid malignancies with prolonged survival.},
  author={Jaroslav V. Frei},
  journal={Cancer},
  year={1992},
  volume={69 5},
  pages={1108-11}
}
DNA flow cytometry was performed on 44 paraffin blocks from 16 specimens of 11 lesions in five patients from two families identified as probably having the dominant gene of the Lynch Type II syndrome. All but one specimen showed diploidy, although two such specimens were metastases and one a recurrence. The one aneuploid gastric biopsy was followed by a… CONTINUE READING