Hereditary influences in oxygen-induced retinopathy in the rat

Abstract

Rodent models of oxygen-induced retinopathy (OIR) provide important insights into the pathogenesis of human retinopathy of prematurity. Herein, we present an overview of our work with rat OIR to date. We have identified marked and consistent variations in susceptibility to OIR amongst different inbred rat strains and provide strong evidence for a genetic… (More)
DOI: 10.1007/s10633-009-9196-3

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