Hereditary hemolytic anemia associated with glucosephosphate isomerase (GPI) deficiency--a new enzyme defect of human erythrocytes.

@article{Baughan1968HereditaryHA,
  title={Hereditary hemolytic anemia associated with glucosephosphate isomerase (GPI) deficiency--a new enzyme defect of human erythrocytes.},
  author={Marjorie A. Baughan and W N Valentine and Donald E. Paglia and P O Ways and Elizabeth R. Simons and Q B DeMarsh},
  journal={Blood},
  year={1968},
  volume={32 2},
  pages={236-49}
}
I N RECENT YEARS, specffic inborn erythrocyte enzyme deficiencies have l)een implicated in the etiology of certain hereditary hemolytic anemias not characterized by spherocytosis. This report defines still another instance in which hereditary hemolytic anemia has been found to be associated with a deficiency in a specific glycolytic enzyme. The propositus has had a hemolytic syndrome present since birth. Erythrocytes and leukocytes both exhibit subnormal activity of the enzyme glucosephosphate… CONTINUE READING