Hereditary gingival fibromatosis: characteristics and novel putative pathogenic mechanisms.

@article{Hkkinen2007HereditaryGF,
  title={Hereditary gingival fibromatosis: characteristics and novel putative pathogenic mechanisms.},
  author={Lari H{\"a}kkinen and Andrea Csiszar},
  journal={Journal of dental research},
  year={2007},
  volume={86 1},
  pages={25-34}
}
Hereditary gingival fibromatosis (HGF) is a rare condition that can occur as an isolated disease or as part of a syndrome or chromosomal abnormality. In severe cases, the gingival enlargement may cover the crowns of teeth and cause severe functional and esthetic concerns. Histological and cell culture studies have uncovered some of the molecular and cellular changes associated with HGF. However, the pathogenesis of the disease is still largely unknown. Recent studies about the genetic… CONTINUE READING