Hereditary fibrinogen A alpha-chain amyloidosis: phenotypic characterization of a systemic disease and the role of liver transplantation.

@article{Stangou2010HereditaryFA,
  title={Hereditary fibrinogen A alpha-chain amyloidosis: phenotypic characterization of a systemic disease and the role of liver transplantation.},
  author={Arie J. Stangou and Nicholas Robert Banner and Bruce M. Hendry and Mohamed Rela and Bernard Portmann and Julia A. Wendon and Mark Monaghan and Philip Maccarthy and Muriel S Buxton-Thomas and Christopher J. Mathias and Juris J. Liepnieks and John O'grady and Nigel David Heaton and Merrill D L Benson},
  journal={Blood},
  year={2010},
  volume={115 15},
  pages={2998-3007}
}
Variants of fibrinogen A alpha-chain (AFib) cause the most common type of hereditary renal amyloidosis in Europe and, possibly, the United States as well. Variant fibrinogen is produced in the liver, and solitary renal allografts fail within 1 to 7 years with recurrent amyloidosis. We assessed 22 AFib patients for combined liver and kidney transplantation (LKT) and report the clinical features and outcome. Twenty-one had E526V and 1, the R554L variant. Coronary atherosclerosis was identified in… CONTINUE READING
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and Transplant

  • NHS Bloo
  • Transplant activity in the UK 2007-2008. UK…
  • 2009

Hereditary fibrinogen A a-chain amyloidosis: clinical features and the curative role of liver transplantation

  • ND Heaton, J O’Grady, M Rela
  • XIth International Symposium on Amyloidosis
  • 2006

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