Hereditary factors in Takayasu disease. III. Polymorphism of human complements.

@article{Numano1989HereditaryFI,
  title={Hereditary factors in Takayasu disease. III. Polymorphism of human complements.},
  author={Fujiki Numano and Kenichi Namba and Kotaro Suzuki and Hiroyuki Matsumoto},
  journal={Experimental and clinical immunogenetics},
  year={1989},
  volume={6 3},
  pages={236-44}
}
Genetic polymorphisms in C2, C4, C6, C7 and BF alleles of human complement were studied in 80 Japanese patients with Takayasu disease, and compared with those of 433 normal Japanese. Statistically significant high frequencies of C4A2 (chi 2: 27.2; p less than 0.01) and C4BQ0 allotype (chi 2: 8.7; p less than 0.01) were found in patients with Takayasu… CONTINUE READING