• DOI:10.1007/s10689-019-00133-9
Corpus ID: 195795956

Hereditary diffuse gastric cancer: cancer risk and the personal cost of preventive surgery

@article{Kaurah2019HereditaryDG,
  title={Hereditary diffuse gastric cancer: cancer risk and the personal cost of preventive surgery},
  author={P. Kaurah and A. Talhouk and A. MacMillan and I. Lewis and K. Chelcun-Schreiber and S. S. Yoon and D. Huntsman},
  journal={Familial Cancer},
  year={2019},
  pages={1-10}
}

• P. Kaurah, A. Talhouk, +4 authors D. Huntsman
• Published 2019
• Medicine
• Familial Cancer

Germline CDH1 mutation carriers are at risk for early-onset diffuse gastric cancer (DGC) and female carriers have an additional risk of lobular breast cancer. The reported literature GC risk of 70% has led to the recommendation for germline mutation carriers to undergo prophylactic total gastrectomy (PTG). The objective of this research was to examine post-surgical clinical outcomes and to identify which of the domains/symptoms from the European Organisation for Research and Treatment of Cancer… Expand

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