Hereditary complete thyroxine-binding globulin deficiency: identification by T3 resin uptake test and DNA analysis.

@article{Noguchi1993HereditaryCT,
  title={Hereditary complete thyroxine-binding globulin deficiency: identification by T3 resin uptake test and DNA analysis.},
  author={Takayuki Noguchi and Ikuo Yamamori and Junki Takamatsu and Takeshi Nakajima and Yasukiyo Mori and Yuichi Kumahara},
  journal={Internal medicine},
  year={1993},
  volume={32 1},
  pages={6-9}
}
Complete thyroxine-binding globulin deficiency (TBG-CD) was uncovered in a subject receiving a comprehensive health examination. The subject had an abnormally high T3 resin uptake. A family study showed that the TBG abnormality had been inherited by X-chromosome linkage. Genetic analysis revealed single nucleotide deletion, common among Japanese with TBG-CD… CONTINUE READING